Prevalence and genetic characterization of diarrhea viruses among cattle in Guangdong, China
BCoV, BNoV, and BRVC exhibited relatively low prevalence levels in Guangdong, China. This is the first study to report the infection rate and genetic characterization of BRVC strains circulating in cattle in China. Our study confirmed that there were disparities in the infection rate regarding sampling site type. Genetic characterization suggested that the identified BCoV strains (GD-GZ-01 and GD-GZ-02) may have originated from Zhejiang or Xinjiang, BNoV (BYN7) could be a novel genetic variant from a Sichuan yak strain, and 22 BRV strains are novel genetic variants in new clusters. And, recombination events between the bovine GD-GZ-01 and the human OC43 strain suggested potential risks of zoonosis. It suggested potential risks of cross-regional and cross-species transmission of these viruses.
Authors
- Wenfen Zhang (ORCID: https://orcid.org/0000-0003-3248-7477)
- Xinhong Pan
- Jun Ma (ORCID: https://orcid.org/0000-0001-9955-4625)
- Zhengkai Wei
- Jingjing Zhang (ORCID: https://orcid.org/0000-0003-0372-4314)
- Juntao Li (ORCID: https://orcid.org/0000-0003-2349-9919)
- Ruixia Xie
- Lixia Xie (ORCID: https://orcid.org/0009-0001-8725-8367)
- Shouyi Chen (ORCID: https://orcid.org/0000-0002-7857-6507)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Southwest University (CN)
- Foshan University (CN)
- Guangzhou Center for Disease Control and Prevention (CN)
- Chinese University of Hong Kong, Shenzhen (CN)
- Shenzhen Pingle Orthopedic Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-10-30
- DOI
- https://doi.org/10.1186/s12917-025-05088-x
- Citations
- 1
- Primary Topic
- Viral gastroenteritis research and epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.40