Diabetes management dilemma: association between glycated hemoglobin levels and mortality risk in diabetic patients

Despite significant improvements in HbA1c control rates among US adults with diabetes from 1999 to 2014, we observed no corresponding reduction in 5-year mortality risks. Achieving HbA1c <7.0% was not associated with lower mortality risk in this population. These findings suggest that improvements in glycemic control alone may be insufficient to reduce mortality in diabetic populations, highlighting the need for a more comprehensive approach to diabetes management.

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Publication Details

Journal
Cardiovascular Diagnosis and Therapy
Published
2025-10-01
DOI
https://doi.org/10.21037/cdt-2025-59
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
Type
article
Field-Weighted Citation Impact
0.00
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article

Diabetes management dilemma: association between glycated hemoglobin levels and mortality risk in diabetic patients

Yongyong Shi, Yong Peng, Yuyang Ye, Yuanning Xu et al.
Cardiovascular Diagnosis and Therapy
Diabetes, Cardiovascular Risks, and Lipoproteins
article

Diabetes management dilemma: association between glycated hemoglobin levels and mortality risk in diabetic patients

Yongyong Shi, Yong Peng, Yuyang Ye, Yuanning Xu, Junwen Wang, Xiaohan Hu, Xuefeng Chen
article en

Abstract

Despite significant improvements in HbA1c control rates among US adults with diabetes from 1999 to 2014, we observed no corresponding reduction in 5-year mortality risks. Achieving HbA1c <7.0% was not associated with lower mortality risk in this population. These findings suggest that improvements in glycemic control alone may be insufficient to reduce mortality in diabetic populations, highlighting the need for a more comprehensive approach to diabetes management.

Cardiovascular Diagnosis and TherapyVol. 15(5)
Sichuan University (CN), West China Hospital of Sichuan University (CN)
Openalex Percentile: Top 57%
Diabetes, Cardiovascular Risks, and Lipoproteins
DOIOpen Access PDFOpenAlex
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Diabetes management dilemma: association between glycated hemoglobin levels and mortality risk in diabetic patients — Yongyong Shi, Yong Peng, et al. · Cardiovascular Diagnosis and Therapy (2025) | TGRS Research Map | TGRS