Testicular teratoma and primary retroperitoneal choriocarcinoma with lung metastasis: a case report

This is the first study that has reported such a rare co-occurrence of male PRC with lung metastasis and testicular mature teratoma diagnosed after puberty. Surgery is the first choice for this case. A thorough evaluation of the retroperitoneal tumor before surgery is critical for the surgeon to pick an appropriate operation program. Immunochemical markers can provide some evidence for the subsequent treatment and prognosis prediction. Very poor prognosis with only 11-month survival time is predicted by both tumors having high percentage of Ki-67 +, the retroperitoneal tumor having vascular and neural invasiveness with lung metastasis, and high malignancy of male PRC at the late stage.

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Publication Details

Journal
AME Case Reports
Published
2025-10-01
DOI
https://doi.org/10.21037/acr-25-44
Primary Topic
Testicular diseases and treatments
Type
article
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0.00
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article

Testicular teratoma and primary retroperitoneal choriocarcinoma with lung metastasis: a case report

Honghong Zhu, Xinru Mao, Zhicheng Wang, Jingping Ge et al.
AME Case Reports
Testicular diseases and treatments
article

Testicular teratoma and primary retroperitoneal choriocarcinoma with lung metastasis: a case report

Honghong Zhu, Xinru Mao, Zhicheng Wang, Jingping Ge, Huan-Bin Hu
article en

Abstract

This is the first study that has reported such a rare co-occurrence of male PRC with lung metastasis and testicular mature teratoma diagnosed after puberty. Surgery is the first choice for this case. A thorough evaluation of the retroperitoneal tumor before surgery is critical for the surgeon to pick an appropriate operation program. Immunochemical markers can provide some evidence for the subsequent treatment and prognosis prediction. Very poor prognosis with only 11-month survival time is predicted by both tumors having high percentage of Ki-67 +, the retroperitoneal tumor having vascular and neural invasiveness with lung metastasis, and high malignancy of male PRC at the late stage.

AME Case ReportsVol. 9
Quzhou City People's Hospital (CN)
Openalex Percentile: Top 51%
Testicular diseases and treatments
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Testicular teratoma and primary retroperitoneal choriocarcinoma with lung metastasis: a case report — Honghong Zhu, Xinru Mao, et al. · AME Case Reports (2025) | TGRS Research Map | TGRS