Multidisciplinary approach to atypical parathyroid tumours and severe hypercalcemia: a case report

APTs and parathyroid carcinomas are challenging entities to delineate in the assessment and management of PHPT. A multidisciplinary approach is crucial to manage severe hypercalcaemia secondary to APTs, as is ongoing surveillance postoperatively, given the potential for multiglandular causes of PHPT. Biochemical differences between APTs and parathyroid carcinomas require further research, although perioperative PTH trends may be useful in differentiating APTs and parathyroid carcinomas prior to resection, and immunohistochemical markers may aid histological differentiation.