Increased Brain-Age Gap in Young Adults With Psychotic Experiences
Young adults who report PEs display an older-looking brain in early adulthood, consistent with atypical brain maturation. However, the gap does not clearly widen or contract by age 30. Multimodal, longitudinal cohorts spanning adolescence to midadulthood are needed to map psychosis-related atypical brain maturation.
Authors
- Pedro Luque-Laguna
- Derek Kenton Jones (ORCID: https://orcid.org/0000-0003-4409-8049)
- Anthony S. David (ORCID: https://orcid.org/0000-0003-0967-774X)
- Rodrigo de Luis‐García (ORCID: https://orcid.org/0000-0001-5023-6490)
- Kate Merritt
- Rafael Navarro‐González (ORCID: https://orcid.org/0000-0002-2900-4107)
Institutions
- Universidad de Valladolid (ES)
- Hospital Clínico Universitario de Valladolid (ES)
- University College London (GB)
- Cardiff University (GB)
Publication Details
- Journal
- Biological Psychiatry Global Open Science
- Published
- 2025-10-30
- DOI
- https://doi.org/10.1016/j.bpsgos.2025.100643
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chongqing Postdoctoral Science Foundation
- Ministerio de Ciencia, Innovación y Universidades
- European Commission
- University of Bristol
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Natural Science Foundation of Chongqing
- Southwest University
- Fok Ying Tung Education Foundation
- Directorate for Biological Sciences
- Medical Research Council
- European Regional Development Fund
- Agencia Estatal de Investigación
- Fundamental Research Funds for the Central Universities
- European Social Fund