Asymmetric kinetic resolution polymerization of racemic <i>O</i> -carboxyanhydride catalyzed by cinchona alkaloids
The enantioselective ring-opening polymerization of <i>O</i>-carboxyanhydride (OCA) has been demonstrated for the first time. Utilizing a cinchona alkaloid derivative featuring a confined chiral pocket, the asymmetric kinetic resolution polymerization (AKRP) of racemic OCA was achieved with a kinetic resolution coefficient (<i>k</i><sub>rel</sub>) up to 9.0, expanding the application scope of AKRP.
Authors
- Guangqiang Xu (ORCID: https://orcid.org/0000-0001-8557-1192)
- Qinggang Wang (ORCID: https://orcid.org/0000-0003-1851-7078)
- Xuanhua Guo (ORCID: https://orcid.org/0000-0003-1221-9133)
- Yanju Jia
- Hongguang Sun (ORCID: https://orcid.org/0000-0002-3246-0939)
- Rulin Yang
Institutions
- Qingdao University of Science and Technology (CN)
- Chinese Academy of Sciences (CN)
- Qinghai New Energy (China) (CN)
- Qingdao Institute of Bioenergy and Bioprocess Technology (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc05378a
- Primary Topic
- Carbon dioxide utilization in catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China