Autoantibodies in <scp>COVID</scp> ‐19 convalescent plasma donors
Our findings suggest that SARS-CoV-2 infection may transiently elevate certain autoantibodies in CCP donors. However, most autoantibody levels decline over time and the overall profiles do not indicate sustained autoreactivity. These results support the immunological safety of CCP, particularly when collected between 60 and 120 days post infection, and highlight the importance of timing in optimizing both efficacy and safety in plasma donation strategies.
Authors
- Primož Rožman (ORCID: https://orcid.org/0000-0002-6466-4039)
- Katerina Jazbec (ORCID: https://orcid.org/0000-0002-7859-289X)
- Elvira Maličev (ORCID: https://orcid.org/0000-0001-8312-1331)
- Klemen Žiberna (ORCID: https://orcid.org/0000-0003-3819-3779)
- Ivica Marić (ORCID: https://orcid.org/0009-0004-9377-0211)
- Polonca Mali
Institutions
- University of Ljubljana (SI)
- Blood Transfusion Centre of Slovenia (SI)
Publication Details
- Journal
- Vox Sanguinis
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1111/vox.70140
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00