Rapid Hemi-Synthesis of Multifunctional Amphiphilic Derivatives Based on Polyphenolic Extractives: Surface Activity, Antioxidant and Antibacterial Properties

Growing concerns within the petrochemical industry regarding the security and sustainability of supply sources have prompted a search for alternative solutions. In this context, research focused on plant-based chemistry aims to develop molecules that can be transformed into new materials, biotechnological tools or industrial alternatives to fossil compounds. In addition, society and cosmetics companies are seeking to simplify formulations. Accordingly, we provide compounds that combine several functionalities, providing 2-in-1 or even 3-in-1 products. We present here a green hemi-synthetic strategy to obtain original polyfunctional derivatives of catechin by grafting fatty acid or fatty-alanine compounds. These bi-modular and tri-modular compounds exhibit surface activity and radical scavenging activity. They show significant antibacterial activity against <i>E. coli</i> as well.