Feasibility of different lymph node metastases delineation approaches in [18F]SiTATE PET/CT imaging in NET patients
The 45% isocontour-thresholding relative to lesional SUV<sub>max</sub> approach constitutes a robust and clinically applicable method for SSTR PET-based tumor delineation in GEPNET patients, irrespective of changes of SSTR avidity of reference tissues (e.g. liver). Further validation is required to establish its role in total tumor volume assessment and therapy monitoring.
Authors
- Simon Lindner (ORCID: https://orcid.org/0000-0003-2424-2066)
- Vera Wenter (ORCID: https://orcid.org/0000-0001-7385-5702)
- Lalith Kumar Shiyam Sundar (ORCID: https://orcid.org/0000-0003-3004-7937)
- Maximilian Scheifele
- Rudolf Alexander Werner (ORCID: https://orcid.org/0000-0003-3372-6046)
- Gabriel T. Sheikh (ORCID: https://orcid.org/0000-0002-7026-9203)
- Christine Spitzweg (ORCID: https://orcid.org/0000-0002-0413-9697)
- Michael Schöll (ORCID: https://orcid.org/0000-0001-7800-1781)
- Franz Josef Gildehaus (ORCID: https://orcid.org/0000-0002-6830-1817)
- Mathias J. Zacherl
- Sophie C. Kunte (ORCID: https://orcid.org/0009-0003-3175-952X)
- Christoph J. Auernhammer
Institutions
- Johns Hopkins University (US)
- University of Siegen (DE)
- Johns Hopkins Medicine (US)
- LMU Klinikum (DE)
- European Neuroendocrine Tumor Society (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- EJNMMI Reports
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s41824-025-00273-5
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00