Sarcoidosis with Trismus Caused by Acute, Progressive Swelling of the Parotid Glands: A Case Report

Sarcoidosis is a systemic granulomatous disease that affects the lungs, lymph nodes, and eyes, which but rarely affects the parotid glands. A 71-year-old Japanese woman developed acute bilateral parotid gland swelling leading to trismus with pain. She also had bilateral swelling of the hilar lymph nodes, suggesting sarcoidosis or lymphoma. A histological examination of a parotid gland biopsy specimen revealed noncaseating granulomas, and sarcoidosis was diagnosed. Treatment with glucocorticoids decreased parotid gland swelling, and trismus and pain resolved. In patients presenting with acute and progressive parotid gland lesions, the possibility of sarcoidosis should be considered.

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Journal
Internal Medicine
Published
2025-01-01
DOI
https://doi.org/10.2169/internalmedicine.6234-25
Primary Topic
Sarcoidosis and Beryllium Toxicity Research
Type
article
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article

Sarcoidosis with Trismus Caused by Acute, Progressive Swelling of the Parotid Glands: A Case Report

Masaaki Nanri, Ryosuke Ikeda, Yuki Kuwahara, Koichiro Takahashi et al.
Internal Medicine
Sarcoidosis and Beryllium Toxicity Research
article

Sarcoidosis with Trismus Caused by Acute, Progressive Swelling of the Parotid Glands: A Case Report

Masaaki Nanri, Ryosuke Ikeda, Yuki Kuwahara, Koichiro Takahashi, Chiho Nakashima, Yoichiro Sugiyama, Natsuko Komiya, Kokoro Kajiwara, Shinsuke Ogusu, Hiroki Tashiro, Yuki Kurihara
article en

Abstract

Sarcoidosis is a systemic granulomatous disease that affects the lungs, lymph nodes, and eyes, which but rarely affects the parotid glands. A 71-year-old Japanese woman developed acute bilateral parotid gland swelling leading to trismus with pain. She also had bilateral swelling of the hilar lymph nodes, suggesting sarcoidosis or lymphoma. A histological examination of a parotid gland biopsy specimen revealed noncaseating granulomas, and sarcoidosis was diagnosed. Treatment with glucocorticoids decreased parotid gland swelling, and trismus and pain resolved. In patients presenting with acute and progressive parotid gland lesions, the possibility of sarcoidosis should be considered.

Internal Medicine
Saga University (JP)
Openalex Percentile: Top 61%
Sarcoidosis and Beryllium Toxicity Research
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Sarcoidosis with Trismus Caused by Acute, Progressive Swelling of the Parotid Glands: A Case Report — Masaaki Nanri, Ryosuke Ikeda, et al. · Internal Medicine (2025) | TGRS Research Map | TGRS