Poststreptococcal Glomerulonephritis Secondary to Bacterial Vaginosis, Complicated by Hemolytic Anemia and Thrombocytopenia: A Case Report
A 65-year-old woman diagnosed with group A streptococcal vaginosis was admitted to our hospital with pyothorax. Abscess drainage was performed, and antimicrobial agents were administered; however, hematuria, proteinuria, hemolytic anemia, thrombocytopenia, and renal dysfunction developed. Conservative management did not improve kidney or systemic conditions. A renal biopsy confirmed post-infectious glomerulonephritis (PIGN). Glucocorticoid treatment improved the kidney and systemic findings. Bacterial vaginosis rarely causes PIGN. Hemolytic anemia and thrombocytopenia are infrequent complications of PIGN, and glucocorticoids may be effective for their treatment.
Authors
- Yasushi Kunisho
- Keisuke Onishi (ORCID: https://orcid.org/0000-0001-9838-6332)
- Hiroaki Nagano (ORCID: https://orcid.org/0000-0001-5587-5662)
- Tadashi Sofue (ORCID: https://orcid.org/0000-0003-1136-8532)
- Yuhei Aoki (ORCID: https://orcid.org/0000-0002-3142-3343)
- Emi Ibuki (ORCID: https://orcid.org/0000-0001-5708-9403)
- Takafumi Shiga
- Masato Higashitani
- Eisuke Nakamura
- Tetsuo Minamino (ORCID: https://orcid.org/0000-0002-5424-4081)
Institutions
- Kagawa University (JP)
Publication Details
- Journal
- Internal Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.2169/internalmedicine.5748-25
- Primary Topic
- Infectious Disease Case Reports and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00