Genomic profiling in hepatocellular carcinoma: a real-world retrospective analysis
This study highlights the genomic landscape of advanced HCC, identifying cell cycle and apoptosis, DNA damage and control, WNT, and p53 as the key affected pathways. Further research is warranted to confirm such findings.
Authors
- F. Piscaglia
- Francesca Salani (ORCID: https://orcid.org/0000-0001-7749-8634)
- Camilla Porta (ORCID: https://orcid.org/0000-0001-8402-6934)
- Emmanuelle Fiore
- A. Casadei Gardini
- Lorenzo Pradelli (ORCID: https://orcid.org/0000-0002-7648-8917)
- Gianluca Masi (ORCID: https://orcid.org/0000-0001-8329-8989)
- U. Malapelle
- Bruno Daniele (ORCID: https://orcid.org/0000-0002-2638-3156)
- Francesca Romana Ponziani (ORCID: https://orcid.org/0000-0002-5924-6238)
- Lorenza Rimassa (ORCID: https://orcid.org/0000-0001-9957-3615)
Institutions
- Humanitas University (IT)
- Vita-Salute San Raffaele University (IT)
- Agostino Gemelli University Polyclinic (IT)
- Roche (Italy) (IT)
- Azienda USL di Bologna (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- IRCCS Humanitas Research Hospital (IT)
- Azienda Ospedaliera Universitaria Pisana (IT)
- University of Naples Federico II (IT)
- University of Bologna (IT)
Publication Details
- Journal
- ESMO Open
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1016/j.esmoop.2025.105879
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00