Integrative Deep Learning of Genomic and Clinical Data for Predicting Treatment Response in Newly Diagnosed Epilepsy
Integrating genomic data with clinical features enhances the ability of deep learning models in predicting ASM response in newly diagnosed epilepsy. This approach may support personalized treatment selection and improve clinical outcomes.
Authors
- Zongyuan Ge (ORCID: https://orcid.org/0000-0002-5880-8673)
- Sarah Barnard (ORCID: https://orcid.org/0000-0003-0517-2533)
- Wei Feng (ORCID: https://orcid.org/0000-0002-7398-6988)
- Terence John O'Brien (ORCID: https://orcid.org/0000-0002-7198-8621)
- Jacqueline A. French (ORCID: https://orcid.org/0000-0003-2242-8027)
- Daniel Thom (ORCID: https://orcid.org/0000-0002-8939-2885)
- Emma Foster (ORCID: https://orcid.org/0000-0001-8958-3844)
- Alison Anderson (ORCID: https://orcid.org/0000-0002-1490-2262)
- Samuel F. Berkovic (ORCID: https://orcid.org/0000-0003-4580-841X)
- Rosemary Burgess (ORCID: https://orcid.org/0000-0002-2664-4395)
- Susannah T. Bellows (ORCID: https://orcid.org/0000-0003-1949-8489)
- Patrick Kwan (ORCID: https://orcid.org/0000-0001-7310-276X)
- Duong Nhu (ORCID: https://orcid.org/0000-0001-9021-9716)
- Robert Zeibich (ORCID: https://orcid.org/0000-0001-6273-7671)
- Zhibin Chen (ORCID: https://orcid.org/0000-0002-1888-6917)
- Mark Howard (ORCID: https://orcid.org/0000-0001-7262-2632)
Institutions
- The Royal Melbourne Hospital (AU)
- Monash Medical Centre (AU)
- NYU Langone Health (US)
- Monash Health (AU)
- Epilepsy Foundation (AU)
- Alfred Health (AU)
- Austin Health (AU)
- Monash University (AU)
- Monash Institute of Medical Research (AU)
Publication Details
- Journal
- Neurology
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1212/wnl.0000000000214315
- Citations
- 3
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.41