Differentiating Incidental From Pathologic Brain MRI Findings in Asymptomatic Boys With X-Linked Adrenoleukodystrophy
Incidental findings were commonly reported during cALD surveillance, possibly reflecting radiologists' intent to differentiate them from cALD. Incidental findings were distinguishable from true cALD lesions based on anatomic location, stability over time, and persistent absence of contrast enhancement. Our findings provide a practical framework for differentiating incidental findings from cALD lesions during surveillance.
Authors
- Sanders Chang (ORCID: https://orcid.org/0000-0003-3543-0310)
- Daniel J. Loes (ORCID: https://orcid.org/0000-0001-7661-3442)
- Danielle Kim (ORCID: https://orcid.org/0000-0002-8136-7095)
- Eric J. Mallack (ORCID: https://orcid.org/0000-0002-2678-8807)
- C Videbaek (ORCID: https://orcid.org/0000-0002-3487-2849)
- Keith Van Haren (ORCID: https://orcid.org/0000-0002-0233-9361)
- Isha N. Srivastava
- Hisham Dahmoush (ORCID: https://orcid.org/0000-0002-9520-6305)
- Jerry C. Cheng (ORCID: https://orcid.org/0000-0001-6574-7883)
- Jeilo Gauna
- Nicole Corwin
Institutions
- Kennedy Krieger Institute (US)
- Kaiser Permanente (US)
- Johns Hopkins University (US)
- Cornell University (US)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Presbyterian Hospital (US)
- Film Independent (US)
- Kaiser Permanente West Los Angeles Medical Center (US)
- Neurological Surgery (US)
- Stanford University (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1212/wnl.0000000000214321
- Citations
- 1
- Primary Topic
- Peroxisome Proliferator-Activated Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.81