ORAL MICROBIOME IN YOUNG PEOPLE DIAGNOSED WITH CHRONIC GENERALIZED PERIODONTITIS BASED IN KAZAN, RUSSIA

Inflammatory periodontal diseases have a multifactorial nature, where the presence of periodontopathogens is the fundamental factor. The study of the periodontal microbiome provides an opportunity for personalized minimally invasive targeted therapy, which in turn increases the effectiveness of treatment and reduces the risk of systemic complications. Description of the study. 483 primary patients who came to a periodontal consultation were examined, and patients who met the study criteria were selected: young age (18–44 years), absence of: somatic pathology, pregnancy and hormonal therapy, use of antibiotics and antiseptics within the last 3 months, smoking and brushing teeth 6 hours before the test; confirmation of the diagnosis: chronic generalized periodontitis of mild or moderate severity. Each patient, after written consent to participate, underwent a clinical, radiological and microbiological examination. Results: In 257 primary patients of young age in Kazan with a diagnosis of chronic generalized periodontitis of mild and moderate severity, the following distribution of microbial forms was revealed: Candida albicans, S. aureus – 24.9% (64) and 18.2% (47), respectively, 12% (31) – Enterobacter genus, 7% (18) – Pseudomonas genus. Such microbial forms as P. gingivalis, Acinetobacter spp., P. micros, K. Pneumoniae and Klebsiella spp. were sown in approximately 4-5% of patients with the specified diagnosis. In the % distribution from 1 to 2% the following representatives of the microbial world were included: B. cerus, S. maltophilia, S. pyogenes, P. Aeruginosa, Actinomyces spp., S. oralis and C. non albicans. The smallest number of patients were infected with E. coli, Citrobacter spp., and Acinetobacter baumanii, each of which was found in less than 1% of patients.