High-grade/large B-cell lymphoma-11q has a very good prognosis in children and young people without a predisposition
High-grade B-cell lymphoma with 11q aberration (HGBCL-11q) is a rare pediatric non-Hodgkin lymphoma. This study assessed outcome in 90 children with HGBCL-11q. With survival rates ≥95%, patients with HGBCL-11q and no predisposition are candidates for deescalated therapy in future prospective trials.
Authors
- Jaime Verdú‐Amorós (ORCID: https://orcid.org/0000-0002-0900-0889)
- Wilhelm Woessmann (ORCID: https://orcid.org/0000-0002-6315-0888)
- Olga Balagué (ORCID: https://orcid.org/0000-0002-5099-3675)
- Daiki Hori (ORCID: https://orcid.org/0000-0003-0634-6961)
- Atsuko Nakazawa (ORCID: https://orcid.org/0000-0002-9008-4281)
- Oussama Abla (ORCID: https://orcid.org/0000-0001-7446-6274)
- Katrin Reutter (ORCID: https://orcid.org/0000-0003-4030-5792)
- Melanie M. Hagleitner (ORCID: https://orcid.org/0000-0001-9424-0352)
- Hannah von Mersi
- Monika Csóka (ORCID: https://orcid.org/0000-0003-4202-891X)
- Birgit Burkhardt (ORCID: https://orcid.org/0000-0002-1151-829X)
- Mara Andrés (ORCID: https://orcid.org/0000-0001-8274-5724)
- Itziar Salaverría (ORCID: https://orcid.org/0000-0002-2427-9822)
- Leila Ronceray
- Minke H. W. Huibers (ORCID: https://orcid.org/0000-0003-0310-3067)
- Gil Gilad
- Lisa Lyngsie Hjalgrim (ORCID: https://orcid.org/0000-0001-5186-3365)
- Andishe Attarbaschi (ORCID: https://orcid.org/0000-0002-9285-6898)
- Ana C. Xavier (ORCID: https://orcid.org/0000-0002-3659-3798)
- Wolfram Klapper (ORCID: https://orcid.org/0000-0001-7208-4117)
- Janez Jazbec
Institutions
- Semmelweis University (HU)
- University of Ljubljana (SI)
- Universität Hamburg (DE)
- Tel Aviv University (IL)
- University of Toronto (CA)
- Hospital for Sick Children (CA)
- Ljubljana University Medical Centre (SI)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Hospital Universitari i Politècnic La Fe (ES)
- University of Alabama at Birmingham (US)
- Hospital Clínico Universitario de Valencia (ES)
- Saitama Children's Medical Center (JP)
- University Hospital Münster (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Schneider Children's Medical Center (IL)
- University Hospital Schleswig-Holstein (DE)
- Sapporo Hokuyu Hospital (JP)
- Hospital Clínic de Barcelona (ES)
- Cancer Research Institute of the Slovak Academy of Sciences (SK)
- Leitat Technological Center (ES)
- St Anna Children's Hospital (AT)
- Princess Máxima Center (NL)
- INCLIVA Health Research Institute (ES)
- Centro de Investigación Biomédica en Red de Cáncer (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Clinical Research Center Kiel (DE)
- Universitat de Barcelona (ES)
- University of Lübeck (DE)
Publication Details
- Journal
- Blood
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1182/blood.2025031086
- Citations
- 1
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.47