The role of carbonic anhydrase I and <scp>II</scp> enzymes in the pathogenesis of gestational diabetes mellitus and their relationship with oxidative stress
Increased CA-I and CA-II levels in GDM patients suggest a potential role for CA enzymes in the metabolic dysregulation associated with GDM. The strong correlation between oxidative stress markers and CA enzyme activity highlights their potential as diagnostic and prognostic biomarkers for GDM. Future studies should explore the mechanistic pathways linking CA enzymes with oxidative stress and insulin resistance to identify novel therapeutic targets.
Authors
- Ayşe Şebnem Erenler (ORCID: https://orcid.org/0000-0002-1786-5022)
- Aysel Alkan Uçkun (ORCID: https://orcid.org/0000-0002-8957-7476)
- Feyza İnceoğlu (ORCID: https://orcid.org/0000-0003-1453-0937)
- Rauf Melekoğlu (ORCID: https://orcid.org/0000-0001-7113-6691)
- Tuğba Raika Kıran (ORCID: https://orcid.org/0000-0002-3724-0249)
Institutions
- Adıyaman University (TR)
- Inonu University (TR)
- Malatya Turgut Özal Üniversitesi (TR)
- Turgut Özal Tıp Merkezi (TR)
- Turgut Özal University (TR)
Publication Details
- Journal
- International Journal of Gynecology & Obstetrics
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1002/ijgo.70591
- Citations
- 2
- Primary Topic
- Enzyme function and inhibition
- Type
- article
- Field-Weighted Citation Impact
- 1.61