Associations Between Right Ventricular Remodeling, Exercise and Circulating Metabolites in Volume and Pressure Overload States
PAH and rTOF exhibited distinct RV remodeling, and PAH, worse exercise tolerance. Differences in circulating branched chain amino acids and one-carbon metabolites were observed among rTOF, PAH, and control subjects.
Authors
- Phong Teck Lee
- Xiaodan Zhao (ORCID: https://orcid.org/0000-0003-1469-8027)
- Jean‐Paul Kovalik (ORCID: https://orcid.org/0000-0003-3654-8193)
- Ru‐San Tan (ORCID: https://orcid.org/0000-0003-2086-6517)
- James Yip (ORCID: https://orcid.org/0000-0001-5470-4554)
- Ju Le Tan (ORCID: https://orcid.org/0000-0001-9822-3277)
- Angela S. Koh (ORCID: https://orcid.org/0000-0001-5629-9732)
- Lynette Teo (ORCID: https://orcid.org/0000-0002-2817-9458)
- Jianhong Ching (ORCID: https://orcid.org/0000-0003-1526-8459)
- Liang Zhong (ORCID: https://orcid.org/0000-0003-3608-4173)
- Ping Chai (ORCID: https://orcid.org/0000-0003-1134-6667)
- Kee Voon Chua (ORCID: https://orcid.org/0000-0001-8702-8230)
- Hai Ning Wee (ORCID: https://orcid.org/0000-0003-2898-0648)
- Shuang Leng
- Sharon Hong Yu Han
- Fei Gao (ORCID: https://orcid.org/0000-0002-0866-7171)
Institutions
- National University of Singapore (SG)
- Singapore General Hospital (SG)
- National University Heart Centre Singapore (SG)
- KK Women's and Children's Hospital (SG)
- Duke-NUS Medical School (SG)
- National University Hospital (SG)
- National Heart Centre Singapore (SG)
Publication Details
- Journal
- JACC Asia
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1016/j.jacasi.2025.09.010
- Citations
- 1
- Primary Topic
- Cardiovascular and exercise physiology
- Type
- article
- Field-Weighted Citation Impact
- 2.38