Validation of the human disharmony loop: Pectoralis minor tenotomy significantly reduces pain and improves function in historically challenging patients who meet reproducible and explicit diagnostic criteria

Patients diagnosed with the Human Disharmony Loop exhibit a dramatic clinical improvement following pectoralis minor release. A medial coracoid pectoralis minor block injection can aid in diagnosis but does not rule-out the syndrome. Patients showed significant reductions in shoulder pain, headaches, concomitant neuropathic lesions and improved shoulder range of motion. Patients should be counseled that some may need secondary neurolysis for residual neuropathy.