Rationale, design and baseline characteristics of the TRANSCEND-CKD trial of retatrutide in patients with chronic kidney disease

TRANSCEND-CKD is designed to provide mechanistic insights on the effects of retatrutide on kidney function and structure, and to inform clinical findings in the ongoing cardio-kidney outcome trial TRIUMPH-Outcomes (NCT06383390).

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Publication Details

Journal
Nephrology Dialysis Transplantation
Published
2025-10-28
DOI
https://doi.org/10.1093/ndt/gfaf230
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
Field-Weighted Citation Impact
0.00

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article

Rationale, design and baseline characteristics of the TRANSCEND-CKD trial of retatrutide in patients with chronic kidney disease

Zvonko Miličević, Hiddo J.L. Heerspink, Petter Bjornstad, Lisette Koeneman et al.
Nephrology Dialysis Transplantation
Chronic Kidney Disease and Diabetes
article

Rationale, design and baseline characteristics of the TRANSCEND-CKD trial of retatrutide in patients with chronic kidney disease

Zvonko Miličević, Hiddo J.L. Heerspink, Petter Bjornstad, Lisette Koeneman, Daniël H. van Raalte, Ilke Tunali, Mathijs C. Bunck, Po-Chang Wu
article en

Abstract

TRANSCEND-CKD is designed to provide mechanistic insights on the effects of retatrutide on kidney function and structure, and to inform clinical findings in the ongoing cardio-kidney outcome trial TRIUMPH-Outcomes (NCT06383390).

Nephrology Dialysis Transplantation
University Medical Center Groningen (NL), Eli Lilly (United States) (US), University of Groningen (NL), University of Washington (US), Somerset Medical Center (US), Amsterdam University Medical Centers (NL)
Eli Lilly and Company
Openalex Percentile: Top 63%
Chronic Kidney Disease and Diabetes
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Rationale, design and baseline characteristics of the TRANSCEND-CKD trial of retatrutide in patients with chronic kidney disease — Zvonko Miličević, Hiddo J.L. Heerspink, et al. · Nephrology Dialysis Transplantation (2025) | TGRS Research Map | TGRS