Transcriptome profiling of uterine leiomyosarcomas identifies a leiomyoma-like expression pattern that indicates better survival
Our results reveal molecular heterogeneity in uterine leiomyosarcomas and provide potential diagnostic and prognostic biomarkers for improved patient management.
Authors
- Esa Pitkänen (ORCID: https://orcid.org/0000-0002-9818-6370)
- Ralf Bützow (ORCID: https://orcid.org/0000-0003-4366-5099)
- Pia Vahteristo (ORCID: https://orcid.org/0000-0002-4615-3825)
- Miika M. Mehine (ORCID: https://orcid.org/0000-0003-0443-0625)
- Sara Khamaiseh (ORCID: https://orcid.org/0000-0001-6868-2341)
- Riitta Koivisto-Korander (ORCID: https://orcid.org/0000-0003-4457-9002)
- Nora E. Schreiber (ORCID: https://orcid.org/0009-0008-5870-9211)
- Terhi Ahvenainen (ORCID: https://orcid.org/0000-0001-9926-5452)
Institutions
- University of Helsinki (FI)
- Helsinki Institute of Physics (FI)
- Helsinki University Hospital (FI)
- Institute for Molecular Medicine Finland (FI)
- Cancer Society of Finland (FI)
Publication Details
- Journal
- BJC Reports
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1038/s44276-025-00190-x
- Primary Topic
- Uterine Myomas and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Association for Cancer Research
- Helsingin Yliopisto
- Suomen Kulttuurirahasto
- Biomedicum Helsinki-säätiö
- Jane ja Aatos Erkon Säätiö
- China Scholarship Council
- Sigrid Juséliuksen Säätiö
- Orionin Tutkimussäätiö
- K. Albin Johanssons Stiftelse
- Syöpäsäätiö