Unusual Localization of Adenoid Cystic Carcinoma: A Case Report of Nasopharyngeal Involvement

Adenoid cystic carcinoma is a malignant tumor of the salivary glands. Its presence in the nasopharynx is rare. It grows slowly but spreads locally and invades nerves. We present the case of a patient aged 62, a smoker, with adenoid cystic carcinoma of the nasopharynx, found first by otorhinolaryngological-specific symptoms and then by neurologic manifestations. MRI showed a tumor in the left posterosuperior wall of the nasopharynx with intracranial extension. Biopsy confirmed the diagnosis; therefore, the patient received combined chemoradiotherapy. The progression of the disease is marked by a distant recurrence after one year of follow-up. The challenge with this rare tumor entity is both diagnostic and therapeutic.

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Publication Details

Journal
Cureus
Published
2025-10-29
DOI
https://doi.org/10.7759/cureus.95678
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
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Unusual Localization of Adenoid Cystic Carcinoma: A Case Report of Nasopharyngeal Involvement

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Salivary Gland Tumors Diagnosis and Treatment
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Unusual Localization of Adenoid Cystic Carcinoma: A Case Report of Nasopharyngeal Involvement

Soufiane Berhili, Nassira Karich, Amal Bennani, Soumiya Samba, Anass Haloui, Loubna Mezouar, Ahmed BenSghier, Mohamed Moukhlissi, Nourelhouda Mouhib
article en

Abstract

Adenoid cystic carcinoma is a malignant tumor of the salivary glands. Its presence in the nasopharynx is rare. It grows slowly but spreads locally and invades nerves. We present the case of a patient aged 62, a smoker, with adenoid cystic carcinoma of the nasopharynx, found first by otorhinolaryngological-specific symptoms and then by neurologic manifestations. MRI showed a tumor in the left posterosuperior wall of the nasopharynx with intracranial extension. Biopsy confirmed the diagnosis; therefore, the patient received combined chemoradiotherapy. The progression of the disease is marked by a distant recurrence after one year of follow-up. The challenge with this rare tumor entity is both diagnostic and therapeutic.

CureusVol. 17(10)
Centre Hospitalier Universitaire Mohammed VI (MA), Mohamed I University (MA)
Openalex Percentile: Top 51%
Salivary Gland Tumors Diagnosis and Treatment
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