Percutaneous Radiofrequency Ablation After Incomplete Adrenalectomy in a Lateralized Case of Primary Aldosteronism

Primary aldosteronism (PA) is a common cause of secondary hypertension. When unilateral aldosterone secretion is identified, surgery is the treatment of choice in most patients and is associated with a high cure rate. Alternative treatments, such as radiofrequency ablation (RFA), are possible options, particularly when surgery is contraindicated. A 56-year-old patient presented with hypertension secondary to PA. A left lateralization was identified after adrenal vein sampling, and the patient underwent a left laparoscopic adrenalectomy. Postoperatively, a residual adrenal remnant was detected incidentally on a computed tomography scan. Persistent PA was confirmed by hormonal workup. To avoid open laparotomy, RFA was proposed as an alternative treatment. The procedure was a biological success, leading to normalization of PA markers. Although adrenalectomy failure is rare, RFA appears to be a possible alternative treatment strategy to prevent the need for repeat surgery and its associated risks.

Authors

Institutions

Publication Details

Journal
JCEM Case Reports
Published
2025-09-27
DOI
https://doi.org/10.1210/jcemcr/luaf251
Primary Topic
Hormonal Regulation and Hypertension
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Percutaneous Radiofrequency Ablation After Incomplete Adrenalectomy in a Lateralized Case of Primary Aldosteronism

Sandrine Eimer, Nicolas Villard, Karim Abid, Tobias Zingg et al.
JCEM Case Reports
Hormonal Regulation and Hypertension
article

Percutaneous Radiofrequency Ablation After Incomplete Adrenalectomy in a Lateralized Case of Primary Aldosteronism

Sandrine Eimer, Nicolas Villard, Karim Abid, Tobias Zingg, Grégoire Wuerzner, Pierre-Antonin Rigon
article en

Abstract

Primary aldosteronism (PA) is a common cause of secondary hypertension. When unilateral aldosterone secretion is identified, surgery is the treatment of choice in most patients and is associated with a high cure rate. Alternative treatments, such as radiofrequency ablation (RFA), are possible options, particularly when surgery is contraindicated. A 56-year-old patient presented with hypertension secondary to PA. A left lateralization was identified after adrenal vein sampling, and the patient underwent a left laparoscopic adrenalectomy. Postoperatively, a residual adrenal remnant was detected incidentally on a computed tomography scan. Persistent PA was confirmed by hormonal workup. To avoid open laparotomy, RFA was proposed as an alternative treatment. The procedure was a biological success, leading to normalization of PA markers. Although adrenalectomy failure is rare, RFA appears to be a possible alternative treatment strategy to prevent the need for repeat surgery and its associated risks.

JCEM Case ReportsVol. 3(12)
Centre Hospitalier Universitaire Vaudois (CH)
Université de Lausanne
Openalex Percentile: Top 57%
Hormonal Regulation and Hypertension
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.