A Pragmatic Trial of Glucocorticoids for Community-Acquired Pneumonia
In patients with CAP in a low-resource setting, adjunctive glucocorticoid therapy was associated with a lower risk of death than standard care. (Funded by Wellcome Trust and others; SONIA PACTR number, PACTR202111481740832; ISRCTN number, ISRCTN36138594.).
Authors
- Beatrice Muthui
- Winston Ongalo
- Bernard Gituma
- Stella Mwakio (ORCID: https://orcid.org/0000-0001-9803-0264)
- Henry Gathuri
- Philip Bejon (ORCID: https://orcid.org/0000-0002-2135-7549)
- Isaac Adembesa
- Nicholas Kirui (ORCID: https://orcid.org/0000-0003-1382-7165)
- Jimmy Shangala
- E. Wangeci Kagucia (ORCID: https://orcid.org/0000-0002-4481-8889)
- Abdirahman I. Abdi (ORCID: https://orcid.org/0000-0001-7989-2125)
- Amos Otedo
- Charles Omondi (ORCID: https://orcid.org/0000-0002-3719-4000)
- Nadia Aliyan (ORCID: https://orcid.org/0000-0001-7046-4108)
- Lucy Ochola (ORCID: https://orcid.org/0000-0003-0264-5526)
- Edwine Barasa (ORCID: https://orcid.org/0000-0001-5793-7177)
- Mike English (ORCID: https://orcid.org/0000-0002-7427-0826)
- Irene Njeri Oginga
- Cyprian Wekesa
- Samuel Akech (ORCID: https://orcid.org/0000-0001-5126-1225)
- Paul Mwaniki (ORCID: https://orcid.org/0000-0003-0359-8426)
- Ruth Lucinde (ORCID: https://orcid.org/0000-0001-6926-8556)
- Steve Biko Okoth
- Mainga Hamaluba (ORCID: https://orcid.org/0000-0002-0266-1414)
- David Mukabi
- Lynda Isaaka (ORCID: https://orcid.org/0000-0003-1589-4134)
- Benedict Orindi (ORCID: https://orcid.org/0000-0002-4601-7890)
- Alvin Wachira
- Evans Manuthu
- Anthony Etyang (ORCID: https://orcid.org/0000-0003-1267-6422)
- Caroline Mithi (ORCID: https://orcid.org/0000-0001-6102-117X)
- Loice Achieng Ombajo (ORCID: https://orcid.org/0000-0003-4632-8792)
- Jared Nyikuli
- Hazel Kariuki
- Hannah Bosire
- Ambrose Agweyu (ORCID: https://orcid.org/0000-0001-8760-1279)
- Dorcas Kamuya (ORCID: https://orcid.org/0000-0001-7107-1736)
- Metrine Saisi
- Elizabeth Isinde
- Isabella Ochola-Oyier
- Edwin Onyango Otieno
- Mohammed Sood
- Patrick Asaava
- Wilberforce Lusamba
- Matiko G. Matiko
- Lillian Mulemi
Institutions
- University of Nairobi (KE)
- Moi University (KE)
- Kenyatta University (KE)
- Nairobi Hospital (KE)
- Kenyatta National Hospital (KE)
- Kenya Medical Research Institute (KE)
- Jaramogi Oginga Odinga University of Science and Technology (KE)
- University of Oxford (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Institute of Primate Research (KE)
- Machakos School (KE)
- Moving the GoalPosts (KE)
- Acıbadem Kadıköy Hospital (TR)
- Kisii University (KE)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1056/nejmoa2507100
- Citations
- 7
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 9.48