The microRNAs landscape of luminal B breast cancer cells in a three-dimensional microenvironment
Overall, this study highlights the utility of 3D cultures in investigating the biology of breast cancer, emphasizing the critical interplay between lncRNAs, miRNAs, and mRNAs. Our findings provide insights into the discovery of novel potential biomarkers, underscoring the importance of integrating both in vitro 3D culture and in vivo expression data for a more accurate identification of miRNAs with possible applications in cancer therapies.
Authors
- Alfredo Hidalgo‐Miranda (ORCID: https://orcid.org/0000-0003-2315-3977)
- María Elizbeth Álvarez-Sánchez (ORCID: https://orcid.org/0000-0002-9212-4451)
- Lorena Aguilar‐Arnal (ORCID: https://orcid.org/0000-0003-4473-4471)
- Jonathan Puente-Rivera (ORCID: https://orcid.org/0000-0001-6941-6248)
- Stephanie I. Núñez-Olvera
- César López‐Camarillo (ORCID: https://orcid.org/0000-0002-9417-2609)
- Laurence A. Marchat (ORCID: https://orcid.org/0000-0003-1615-8614)
- Karla Rubio (ORCID: https://orcid.org/0000-0002-8337-3106)
- Yarely M. Salinas-Vera (ORCID: https://orcid.org/0000-0003-2129-9980)
- Mireya Cisneros-Villanueva (ORCID: https://orcid.org/0000-0002-5662-0247)
Institutions
- Universidad Autónoma de la Ciudad de México (MX)
- National Institute of Genomic Medicine (MX)
- Instituto de Medicina Genómica (ES)
- Hospital Juárez de México (MX)
- Instituto Politécnico Nacional (MX)
- Benemérita Universidad Autónoma de Puebla (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Hereditas
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s41065-025-00586-2
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universidad Nacional Autónoma de México