Dental implant-associated oral squamous cell carcinoma: a clinical retrospective study of 22 cases

OSCC after dental implant placement, though uncommon, is a significant clinical issue due to its late diagnosis, aggressive bone invasion, and poor prognosis. Our findings underscore the importance of differentiating OSCC from peri-implantitis and recommend prompt biopsy when peri-implant inflammation persists despite conventional treatment. Early recognition may improve survival outcomes. The observed links with prior malignancy, chronic inflammation, and lifestyle risk factors suggest a multifactorial etiology, highlighting the need for further longitudinal studies to refine prevention and early detection strategies.