KLOTHO-VS heterozygosity, α-klotho protein levels and cognitive performance in Alzheimer’s disease
KL-VS heterozygosity may be linked to lower likelihood of classification as aMCI or dementia due to AD, and its association with memory might be specific to the aMCI stage of AD and modulated by APOE ε4 status.
Authors
- Tereza Kolářová
- Alžběta Katonová (ORCID: https://orcid.org/0009-0006-5605-7200)
- Hana Horáková (ORCID: https://orcid.org/0000-0003-4192-1423)
- Martin Vyhnálek (ORCID: https://orcid.org/0000-0002-5976-4932)
- Kateřina Veverová (ORCID: https://orcid.org/0000-0002-5845-1854)
- Ross Andel (ORCID: https://orcid.org/0000-0003-4083-4790)
- Jakub Hort (ORCID: https://orcid.org/0000-0002-1080-3726)
- Vanesa Jurasova
- Václav Maťoška (ORCID: https://orcid.org/0009-0005-3459-6193)
- Šárka Borovská (ORCID: https://orcid.org/0009-0001-5143-3549)
Institutions
- Charles University (CZ)
- University Hospital in Motol (CZ)
- Na Homolce Hospital (CZ)
- Arizona State University (US)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s13195-025-01878-5
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00