A rare case of cellular angiofibroma with sarcomatous transformation occurred in the popliteal fossa
This report highlights a rare and extraordinary case of CAS identified in the popliteal fossa. Through NGS, we had identified concurrent deletions of the RB1 and TP53 genes. Although the prognosis of this case was slightly worse than that reported in the literature, it provides additional evidence for expanding the known anatomical range of CAF.
Authors
- Lina Zhao
- Yan Honglin
- Hua He (ORCID: https://orcid.org/0000-0001-8461-922X)
- Juan Zeng (ORCID: https://orcid.org/0000-0002-2366-9327)
- Yuan Ji (ORCID: https://orcid.org/0000-0002-2631-9082)
- Jingyu Ren (ORCID: https://orcid.org/0000-0002-0048-3052)
- Yajun Cao (ORCID: https://orcid.org/0000-0002-6004-1416)
- Zhenyu Liu (ORCID: https://orcid.org/0000-0001-7559-8519)
- Feng Guan
Institutions
- Dalian Medical University (CN)
- Xinjiang Production and Construction Corps (CN)
- Wuhan University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
- Renmin Hospital of Wuhan University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1007/s12672-025-03826-z
- Primary Topic
- Urologic and reproductive health conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Hubei Province
- Wuhan University
- Renmin Hospital of Wuhan University