Organocopper Derivative of Nitronyl Nitroxide Stabilized with N-Heterocyclic Carbene

A novel nitronyl nitroxide organocopper derivative has been reported─a unique reagent for cross-coupling reactions of aryl and heteroaryl halides. The innovative protocol involves a copper complex supported by a sterically hindered NHC ligand, specifically SIPrCuNN, and a Pd(0)-catalytic system resulting from Pd2dba3·CHCl3 and the phosphine ligand MeCgPPh. The designed method is compatible with various aromatic and heteroaromatic iodides, therefore increasing new applications for creating functionalized nitronyl nitroxide paramagnet and open-shell compounds.