Thyroid hormone receptor α signaling shapes innate and adaptive immune responses during viral infection
The present study demonstrates a complex role of TRα signaling in protective immune responses during disease, with distinct effects on innate and adaptive immune cells. By exploring the understudied link between the endocrine and immune systems, this study provides novel evidence for the role of TH as modulators of immunity.
Authors
- Lars C. Moeller (ORCID: https://orcid.org/0000-0002-9330-9036)
- Robert Klopfleisch (ORCID: https://orcid.org/0000-0002-6308-0568)
- Torben Knuschke (ORCID: https://orcid.org/0000-0002-2273-1475)
- Anita Boelen (ORCID: https://orcid.org/0000-0002-4994-2918)
- Astrid Maria Westendorf (ORCID: https://orcid.org/0000-0002-2121-2892)
- Georg Sebastian Hönes (ORCID: https://orcid.org/0000-0002-5080-7166)
- Denise Zwanziger (ORCID: https://orcid.org/0000-0002-4556-0541)
- Heike Heuer (ORCID: https://orcid.org/0000-0001-7094-6959)
- Christina Wenzek (ORCID: https://orcid.org/0000-0002-9693-4400)
- Dagmar Führer
Institutions
- Amsterdam Neuroscience (NL)
- University of Duisburg-Essen (DE)
- Freie Universität Berlin (DE)
- University of Amsterdam (NL)
Publication Details
- Journal
- European Thyroid Journal
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1530/etj-25-0156
- Citations
- 1
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.29