The Cognitive and Neuroimaging for Neurodegenerative Disorders Study (CogNID): design and initial findings from real-world clinical practice
The CogNID study highlights the clinical and diagnostic heterogeneity of individuals with cognitive impairment, particularly in younger adults. Incorporating neuroimaging and CSF biomarkers into routine clinical pathways enhances diagnostic precision and reveals distinct phenotypic profiles between EOCD and LOCD. These findings underscore the need for harmonised diagnostic protocols, broader biomarker accessibility, and inclusive recruitment strategies in dementia research and clinical services.
Authors
- Elizabeta B. Mukaetova‐Ladinska (ORCID: https://orcid.org/0000-0003-0817-7591)
- Bruno Gran (ORCID: https://orcid.org/0000-0001-6384-2342)
- Akram A. Hosseini (ORCID: https://orcid.org/0000-0003-0133-9842)
- Permesh Singh Dhillon (ORCID: https://orcid.org/0000-0003-4353-4515)
- Peter Sellars (ORCID: https://orcid.org/0000-0002-0878-2794)
- JeYoung Jung (ORCID: https://orcid.org/0000-0003-3739-7331)
- Kehinde Junaid (ORCID: https://orcid.org/0000-0001-5986-395X)
- Ann J. Lee (ORCID: https://orcid.org/0009-0002-5493-3220)
- Beili Shao
- Hannah Sargisson
Institutions
- Nottingham University Hospitals NHS Trust (GB)
- University of Nottingham (GB)
- University of Leicester (GB)
- Leicester General Hospital (GB)
- Nottinghamshire Healthcare NHS Foundation Trust (GB)
- Institute of Mental Health (GB)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-10-29
- DOI
- https://doi.org/10.3389/fpsyt.2025.1630082
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical Research Council