Sex-Specific Determinants of the Ketone Body β-Hydroxybutyrate in the General Population
A complex interplay of metabolic, hormonal, and lifestyle factors are associated with BHB levels in the general population, with distinct sex differences. In women, hormonal status was the most important factor, while in men increasing age was the most significant factor affecting BHB levels.
Authors
- Margery A. Connelly (ORCID: https://orcid.org/0000-0002-3917-592X)
- Ron T. Gansevoort (ORCID: https://orcid.org/0000-0002-3223-0906)
- Lyanne M. Kieneker (ORCID: https://orcid.org/0000-0002-8028-6488)
- Roman-Ulrich Müller (ORCID: https://orcid.org/0000-0001-6910-0745)
- Martine Knol (ORCID: https://orcid.org/0009-0007-1780-4899)
- Stephan J. L. Bakker (ORCID: https://orcid.org/0000-0003-3356-6791)
- Markus Matthias Rinschen (ORCID: https://orcid.org/0000-0002-9252-1342)
- Amarens van der Vaart (ORCID: https://orcid.org/0000-0002-9149-184X)
- Maatje D.A. van Gastel (ORCID: https://orcid.org/0000-0002-2418-7039)
Institutions
- University Medical Center Groningen (NL)
- Universität Hamburg (DE)
- University of Groningen (NL)
- University of Cologne (DE)
- Aarhus University (DK)
- LabCorp (United States) (US)
- Aarhus University Hospital (DK)
- University Medical Center Hamburg-Eppendorf (DE)
- University Hospital Cologne (DE)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1210/clinem/dgaf587
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Nierstichting
- Universitair Medisch Centrum Groningen