Acanthamoeba castellanii cysteine protease 3 promotes M1 macrophage polarization through the TLR4/NF‑κB pathway
AcCP3 promotes M1 macrophage polarization through the TLR4/NF-κB pathway and may exacerbate inflammation through upregulating pro-inflammatory cytokines.
Authors
- Hailong Wang (ORCID: https://orcid.org/0000-0003-3751-3283)
- Hongli Liu (ORCID: https://orcid.org/0000-0002-3479-3315)
- Yong Yang (ORCID: https://orcid.org/0000-0002-2841-8420)
- Mengdi Wang (ORCID: https://orcid.org/0000-0002-2101-9507)
- Zhixin Wang (ORCID: https://orcid.org/0000-0003-2350-735X)
- Weiwei Jiao (ORCID: https://orcid.org/0009-0008-5279-7740)
Institutions
- Shanxi Medical University (CN)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s13071-025-07060-y
- Citations
- 1
- Primary Topic
- Legionella and Acanthamoeba research
- Type
- article
- Field-Weighted Citation Impact
- 1.80
Funders
- Fudan University
- Shanxi Medical University