Prognostic model for pediatric brain tumors based on tumor microenvironment-specific gene signatures
The TME-specific gene-based prognostic model effectively predicts survival outcomes in pediatric brain tumors, offering promising biomarkers for personalized medicine and potential therapeutic targets. However, further research is required to validate these findings across different tumor subtypes and to explore their clinical applications.
Authors
- Alexander N. Chernov (ORCID: https://orcid.org/0000-0003-2464-7370)
- Yuxin Liu (ORCID: https://orcid.org/0009-0002-2723-9356)
- Lina Sang (ORCID: https://orcid.org/0000-0003-4837-7408)
- Guodong Liu (ORCID: https://orcid.org/0000-0001-8683-0803)
- Tao Jiang (ORCID: https://orcid.org/0000-0002-9205-8183)
- Guanjian Zhao
Institutions
- Capital Medical University (CN)
- Dalian Medical University (CN)
- Northwest University (CN)
- Beijing Tian Tan Hospital (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Institute of Experimental Medicine (RU)
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1007/s12672-025-03754-y
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Centre Scientifique et Technique du Bâtiment