A multi-center study for colorectal cancer early detection in high-risk disease patients using cell-free fragmentomics assay
This multi-center study underscores a significant advancement in liquid biopsy technology, offering a highly accurate and non-invasive approach for early CRC detection and differentiation of advanced colorectal adenomas.
Authors
- Chao Ding (ORCID: https://orcid.org/0009-0009-0266-6416)
- Qionghong Xie (ORCID: https://orcid.org/0000-0002-6189-2909)
- Xiuxiu Xu (ORCID: https://orcid.org/0000-0003-4199-7874)
- Linjie Zhang (ORCID: https://orcid.org/0000-0001-5150-5840)
- Ruowei Yang (ORCID: https://orcid.org/0000-0002-6438-4635)
- Qinggang Yuan
- Lingling Yang (ORCID: https://orcid.org/0000-0002-0976-2090)
- Yongle Li (ORCID: https://orcid.org/0000-0001-9879-0626)
- Hua Bao (ORCID: https://orcid.org/0000-0001-5774-8755)
- Deqing Wu (ORCID: https://orcid.org/0000-0003-3047-7996)
- Bing Gu (ORCID: https://orcid.org/0000-0001-7764-3213)
- Feng Zhu (ORCID: https://orcid.org/0000-0002-4688-5604)
- Kai Wang (ORCID: https://orcid.org/0000-0003-0553-5293)
- Jing Zhou (ORCID: https://orcid.org/0000-0001-5844-6126)
- Jierong Chen
- Guansheng Zheng
- Zhongwen Zheng
- Zejian Lyu
- Waiting Lam
- Lishu Xu (ORCID: https://orcid.org/0000-0001-8035-3081)
- Dongqin Zhu
Institutions
- Nanjing University of Chinese Medicine (CN)
- Sun Yat-sen University (CN)
- Xuzhou Medical College (CN)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Kingmed Diagnostics (CN)
- Nanjing Drum Tower Hospital (CN)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s12935-025-03967-9
- Citations
- 1
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Natural Science Foundation of China
- Guangdong Provincial People's Hospital
- National Key Research and Development Program of China
- Basic and Applied Basic Research Foundation of Guangdong Province