Molecular epidemiology of high-risk human papillomavirus infection and its predictive factors among women living with HIV in Northeast Ethiopia: a facility-based cross-sectional study

The study revealed a significantly higher prevalence of hrHPV among HIV-positive women in Dessie and Kombolcha cities. The non-16/18 hrHPV genotype was the more frequent compared to HPV 16 and 18. Predictive factors for hrHPV infection included multiple sexual partners, non-use of condoms, history of sexually transmitted infections, short duration on ART, low CD4 counts, and high viral loads. To reduce this risk, ART programs should incorporate cervical cancer screening, promote HPV vaccination, and strengthen sexual health education.

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Publication Details

Journal
BMC Infectious Diseases
Published
2025-10-29
DOI
https://doi.org/10.1186/s12879-025-11853-y
Citations
1
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
1.35
Controls
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article

Molecular epidemiology of high-risk human papillomavirus infection and its predictive factors among women living with HIV in Northeast Ethiopia: a facility-based cross-sectional study

Genet Molla, Yonas Erkihun, Bantamlak Getachew, Alemu Gedefie et al.
1 citations
BMC Infectious Diseases
Cervical Cancer and HPV Research
1.35
article

Molecular epidemiology of high-risk human papillomavirus infection and its predictive factors among women living with HIV in Northeast Ethiopia: a facility-based cross-sectional study

Genet Molla, Yonas Erkihun, Bantamlak Getachew, Alemu Gedefie, Yemane Eshetu, Saleamlak Sebsibe, Agumas Shibabaw
article en
1 citations

Abstract

The study revealed a significantly higher prevalence of hrHPV among HIV-positive women in Dessie and Kombolcha cities. The non-16/18 hrHPV genotype was the more frequent compared to HPV 16 and 18. Predictive factors for hrHPV infection included multiple sexual partners, non-use of condoms, history of sexually transmitted infections, short duration on ART, low CD4 counts, and high viral loads. To reduce this risk, ART programs should incorporate cervical cancer screening, promote HPV vaccination, and strengthen sexual health education.

BMC Infectious DiseasesVol. 25(1)
Wollo University (ET)
Openalex Percentile: Top 14%
Cervical Cancer and HPV Research
1.35
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