Genome-wide investigation of the dmrt gene family reveals new insight into the gonad development in Plectropomus leopardus: dmrt2a regulate the development of oocytes
This study demonstrates that dmrt2a plays a crucial regulatory role in the development of the oocytes in P. leopardus, supplementing the understanding of the functional roles of the dmrt gene family in vertebrate sex differentiation. These findings will help to understand the properties and functions of the dmrt genes in P. leopardus and provide a solid basis for further studies on the functional mechanisms of dmrt genes in hermaphroditic fish.
Authors
- Hui Ding (ORCID: https://orcid.org/0000-0001-9293-6778)
- Jiashuo Li (ORCID: https://orcid.org/0000-0002-2915-4770)
- Jiayi Wu (ORCID: https://orcid.org/0000-0002-4819-2190)
- Qi Guo (ORCID: https://orcid.org/0000-0001-8280-7518)
- Bó Wáng (ORCID: https://orcid.org/0000-0002-8001-9937)
- Jingwen Wang (ORCID: https://orcid.org/0000-0002-1405-4697)
- Jingjie Hu (ORCID: https://orcid.org/0000-0002-0715-7137)
- Zhenmin Bao (ORCID: https://orcid.org/0000-0001-6126-0509)
- Peiyu Li (ORCID: https://orcid.org/0000-0002-1001-7485)
- Chenggang Yin
Institutions
- Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) (CN)
- Ocean University of China (CN)
- Hainan Tropical Ocean University (CN)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s13293-025-00769-6
- Citations
- 3
- Primary Topic
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 5.45
Funders
- National Natural Science Foundation of China