Optimizing steroid treatment for UC patients with CMV colitis: a multicenter real-world study
Steroid strategies for UC with CMV colitis require context-specific adjustments based on baseline steroid exposure. Intensified treatment outperforms steroid non-initiation in improving short-term response and reducing long-term colectomy risk, while showing no inferiority to tapering. Individualized therapy balancing immediate and long-term outcomes is critical.
Authors
- Xiaoyin Bai (ORCID: https://orcid.org/0000-0002-9092-7592)
- Haozheng Liang
- Hong Yang (ORCID: https://orcid.org/0000-0002-2986-7324)
- Wei Han (ORCID: https://orcid.org/0000-0001-6848-6439)
- Linglin Tian
- Xiaowei Xue (ORCID: https://orcid.org/0000-0002-0719-6996)
- Weiyang Zheng
- Gechong Ruan
Institutions
- Shanxi Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- First Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s12985-025-02948-8
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Peking Union Medical College Hospital