Correlation between antimicrobial resistance and virulence in carbapenem-resistant Klebsiella pneumoniae at colonization and infection stages
CRKP maintains stable resistance genes during colonization-infection transitions, but dynamic virulence changes indicate higher infection risks when colonization converts to infection. Enhanced monitoring of virulence and resistance is critical to control hv-CRKP spread in ICUs.
Authors
- Ning Xie (ORCID: https://orcid.org/0000-0002-1491-6269)
- X. Liang
- Yongfang Liu
- Guixia Wang (ORCID: https://orcid.org/0000-0002-3824-0478)
- Cheng Li (ORCID: https://orcid.org/0000-0003-3424-2414)
- Peilin Zhang (ORCID: https://orcid.org/0000-0003-3874-4948)
- Yijie Yin (ORCID: https://orcid.org/0009-0007-1818-0002)
- Junning He
Institutions
- North Sichuan Medical University (CN)
- Third People's Hospital of Chengdu (CN)
- Affiliated Hospital of North Sichuan Medical College (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s12879-025-11902-6
- Citations
- 1
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.59