Virome of canine lymph nodes: identification of viruses with zoonotic potential
This research not only elucidates the remarkable diversity of the virome within canine lymph node tissues but also employs phylogenetic analysis to delineate the evolutionary relationships between these viruses and previously documented strains. Notably, this study represents the first identification of parvoviruses and circoviruses in canine lymph nodes that exhibit high sequence homology with human viral strains, suggesting that these canine-derived and human-associated viruses may have diverged from a common ancestor.
Authors
- Hongfeng Yang (ORCID: https://orcid.org/0000-0002-5925-6487)
- Tongling Shan (ORCID: https://orcid.org/0000-0002-5329-6349)
- Likai Ji (ORCID: https://orcid.org/0009-0007-0411-7774)
- Ping Wu (ORCID: https://orcid.org/0000-0003-2664-8502)
- Quan Shen (ORCID: https://orcid.org/0000-0001-9041-8475)
- Yuwei Liu (ORCID: https://orcid.org/0000-0001-7373-2868)
- Xiaochun Wang
- Yue Chen (ORCID: https://orcid.org/0000-0002-2502-9518)
- Shiyin Huang
- Xiaojü Lu (ORCID: https://orcid.org/0000-0002-2216-5004)
- Shixing Yang
- Wen Zhang (ORCID: https://orcid.org/0009-0008-1519-4692)
Institutions
- Jiangsu University (CN)
- Shanghai Veterinary Research Institute (CN)
- Affiliated Hospital of Jiangsu University (CN)
- Chinese Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s12985-025-02972-8
- Primary Topic
- Animal Virus Infections Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Beijing Institute of Genomics, Chinese Academy of Sciences