Pitfalls in the Serologic Diagnosis of Maternal Syphilis: A Case Series
Pregnancy is associated with false-positive treponemal and nontreponemal screening test results. We present five pregnant women who had reactive treponemal screening and nontreponemal tests but nonreactive Treponema pallidum-Particle Agglutination test. Reliance on treponemal screening tests may result in misdiagnosis and unnecessary treatment unless a specific treponemal test is performed.
Authors
- Traci Pifer
- Pablo J. Sánchez (ORCID: https://orcid.org/0000-0003-2437-1247)
- Tanisha R. Pettus
- Sebastián Martínez (ORCID: https://orcid.org/0000-0002-7651-6674)
- Charles A. Miller (ORCID: https://orcid.org/0000-0002-3813-1706)
- B. Jones (ORCID: https://orcid.org/0000-0003-1745-284X)
- S. Chand
- Regent Epperson
Institutions
- Nationwide Children's Hospital (US)
- GTx (United States) (US)
- Medical Protective (US)
- Ohio Department of Health (US)
- Kleijnen Systematic Reviews (United Kingdom) (GB)
- Institute for Clinical and Economic Review (US)
- The Ohio State University (US)
- Reed College (US)
- Toto (Japan) (JP)
Publication Details
- Journal
- Sexually Transmitted Diseases
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1097/olq.0000000000002261
- Primary Topic
- Syphilis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00