Multi-pronged surveillance to understand the spatiotemporal correlations among macaques, vectors and humans in Plasmodium knowlesi malaria transmission
A key finding from this study is that the proportion of P. knowlesi infection in macaques may serve as a useful proxy for persistent transmission in an area, potentially indicating increased risk of human infection in nearby communities. This highlights the value of wildlife surveillance in predicting and managing zoonotic malaria risk. Integrating insights from epidemiology, ecology, veterinary science and public health is essential for effectively controlling zoonotic diseases such as P. knowlesi malaria and reducing their impact on both human and animal populations.
Authors
- Zailiza Suli (ORCID: https://orcid.org/0000-0003-2036-9318)
- Mohd Hafizi bin Abdul Hamid
- Mohd Lutfi Abdullah (ORCID: https://orcid.org/0000-0002-3472-9858)
- Sandthya Pramasivan
- Nantha Kumar Jeyaprakasam (ORCID: https://orcid.org/0000-0002-5526-9934)
- Ting‐Wu Chuang (ORCID: https://orcid.org/0000-0001-8359-8172)
- Jenn Zhueng Tam
- Wang Nguitragool (ORCID: https://orcid.org/0000-0002-5484-7130)
- Yee Ling Lau (ORCID: https://orcid.org/0000-0002-2037-2165)
- Indra Vythilingam (ORCID: https://orcid.org/0000-0003-3952-7996)
- Wei Kit Phang
- Anis Adlina Binti Isman Rohimly
- Norsharina Binti Ashrat
Institutions
- Ministry of Health (MY)
- Mahidol University (TH)
- Department of National Parks Wildlife and Plant Conservation (TH)
- University of Malaya (MY)
- Mahidol Oxford Tropical Medicine Research Unit (TH)
- Taipei Medical University (TW)
- National University of Malaysia (MY)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s13071-025-07082-6
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Mahidol University
- National Science and Technology Council
- National Institutes of Health