Optimizing LED photobiomodulation parameters to prevent cartilage matrix degradation in knee osteoarthritis: in vitro and in vivo study
LED therapy at 940 nm with 52 J/cm<sup>2</sup> attenuates ECM degradation and pain in KOA, defining a target LED parameter set for potential clinical translation.
Authors
- Siu Ngor Fu (ORCID: https://orcid.org/0000-0003-4405-015X)
- Peng Xia (ORCID: https://orcid.org/0000-0003-3891-3385)
- Safayet Ahmed (ORCID: https://orcid.org/0000-0003-3292-3929)
- Ye Li (ORCID: https://orcid.org/0000-0002-2481-6894)
- Tianxiang Fan (ORCID: https://orcid.org/0000-0003-3781-924X)
Institutions
- Oregon State University (US)
- Hong Kong Polytechnic University (HK)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s13018-025-06341-7
- Primary Topic
- Laser Applications in Dentistry and Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hong Kong Polytechnic University