Wound-induced eyespots on butterfly wings at the intersection of immune response and pigmentation development
Our findings reveal that immune activation contributes to the development of wound-induced eyespots and impacts both pigmentation pattern formation and wing size regulation. These results underscore the complex interplay between immune function and developmental processes and provide new insights into the origins of lineage-specific morphological innovations. Future studies will address the cellular and molecular mechanisms behind the effects of immune activation on pigmentation development.
Authors
- David Duneau (ORCID: https://orcid.org/0000-0002-8323-1511)
- Guilherme Wagner Gutierrez Atencio (ORCID: https://orcid.org/0000-0001-6743-0951)
- Ana Rita Garizo (ORCID: https://orcid.org/0000-0003-3399-5844)
- Patrícia Beldade (ORCID: https://orcid.org/0000-0001-7831-979X)
- Maria Adelina Gonçalves Jerónimo
Institutions
- Sustainability Institute (ZA)
- The Queen's Medical Research Institute (GB)
- Instituto Gulbenkian de Ciência (PT)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s12915-025-02397-3
- Primary Topic
- Developmental Biology and Gene Regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Fundação para a Ciência e a Tecnologia