The mediation of circulating inflammatory proteins in the causal pathway from immune cells to osteoarthritis
This study provides a comprehensive investigation of the causal relationships between immune cells and Knee OA, and estimates the mediating role of circulating inflammatory proteins. These findings contribute to identifying high-risk populations for OA and offer new insights for early prevention and clinical intervention.
Authors
- Yanrong Liu
- Ye Yuan (ORCID: https://orcid.org/0000-0002-8576-9016)
- Xinjun Liang (ORCID: https://orcid.org/0000-0002-5180-7926)
- Sining Kang
Institutions
- Shanxi Medical University (CN)
- First Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s13018-025-06374-y
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00