Analysis of factors affecting smooth extubation in delayed extubation patients following intracranial surgery: an ambispective cohort study
Of 157 patients (mean BMI 23.88 ± 3.25 kg/m<sup>2</sup>, 33.1% male), adverse extubation occurred in 80 (51.0%). Univariate analysis showed several significant variables (P < 0.05): age, FOUR<sub>E</sub>, FOUR<sub>M</sub>, airway patency, Duration from command obedience to extubation, time to extubate, types of surgical procedure, operation duration, intraoperative propofol use, sedation before. Multivariate analysis showed: age [OR = 2.791, 95%CI (1.268, 6.147)], intraoperative propofol use [OR = 0.298, 95%CI (0.012, 0.796)], preoperative airway patency [OR = 2.463, 95%CI (1.159, 5.234)], time to extubate [OR = 7.884, 95%CI (1.337, 46.472)] as independent factors of dverse extubation.
Authors
- Xueli Yang (ORCID: https://orcid.org/0000-0002-8373-4389)
- Yuhong Li (ORCID: https://orcid.org/0000-0001-5688-9740)
- Tunan Chen (ORCID: https://orcid.org/0000-0003-0460-5632)
- Yan Liu (ORCID: https://orcid.org/0000-0002-2566-6867)
- Rui Wang (ORCID: https://orcid.org/0000-0003-1723-4746)
- Xia Zhang (ORCID: https://orcid.org/0009-0001-5748-4371)
- Chao Zhang (ORCID: https://orcid.org/0000-0003-1840-3011)
- Weina Li (ORCID: https://orcid.org/0009-0004-2094-1964)
- Feilong Wang (ORCID: https://orcid.org/0000-0003-4607-3574)
- Binbin Tan (ORCID: https://orcid.org/0000-0002-5777-4862)
- Jishu Xian (ORCID: https://orcid.org/0000-0001-5028-7562)
Institutions
- Army Medical University (CN)
- Southwest Hospital (CN)
Publication Details
- Journal
- BMC Anesthesiology
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s12871-025-03394-3
- Citations
- 3
- Primary Topic
- Intraoperative Neuromonitoring and Anesthetic Effects
- Type
- article
- Field-Weighted Citation Impact
- 6.02