Impact of a molecular syndromic panel on <i>Clostridioides difficile</i> detection and clinical interpretation
After implementation of a molecular syndromic panel for infectious diarrhea, a significantly greater proportion of <i>C. difficile</i> results were classified as colonization rather than infection compared to the pre-implementation period. Routine <i>C. difficile</i> reporting from multiplex panels should be re-evaluated to minimize diagnostic uncertainty in some patients.
Authors
- Colin Lee (ORCID: https://orcid.org/0000-0002-1031-3065)
- Christopher F. Lowe (ORCID: https://orcid.org/0000-0001-9320-4499)
- Shayan Shakeraneh
- Nancy Matic (ORCID: https://orcid.org/0000-0002-4158-6955)
- Victor C. M. Leung (ORCID: https://orcid.org/0000-0003-3529-2640)
- Marc G. Romney (ORCID: https://orcid.org/0000-0001-6017-4246)
- Jennifer Bilawka
- Willson Jang
- Aleksandra Stefanovic (ORCID: https://orcid.org/0000-0001-9299-2040)
- Leah Gowland
- Michael Payne (ORCID: https://orcid.org/0009-0002-3677-9776)
Institutions
- Providence Health Care (CA)
Publication Details
- Journal
- Infection Control and Hospital Epidemiology
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1017/ice.2025.10313
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 0.00