Effectiveness of Arthrocentesis versus Platelet-Rich Plasma Injections in TMJ Disorders: A Clinical Study

Background: Temporomandibular joint (TMJ) disorders affect a significant proportion of the population, leading to pain, joint dysfunction, and reduced quality of life. Arthrocentesis and platelet-rich plasma (PRP) injections are two widely used conservative treatments. This study aims to compare the effectiveness of arthrocentesis and PRP in improving pain relief, mouth opening, and functional outcomes in TMJ disorder patients. Methods: A total of 60 patients diagnosed with TMJ disorders were enrolled and divided into two groups ( n = 30 each). Group A underwent arthrocentesis, while Group B received PRP injections. Outcomes were measured based on pain reduction (VAS score), maximum mouth opening (maximum mouth opening [MMO] in mm), and functional improvement using the Jaw Function Limitation Scale. Measurements were recorded at baseline, 1 month, and 3 months post-treatment. Statistical analysis was conducted using paired t -tests and analysis of variance (ANOVA). Results: Both treatment groups showed significant improvement. The PRP group demonstrated superior long-term pain relief (VAS: 7.2 to 2.1) compared to arthrocentesis (VAS: 7.4 to 3.5) at 3 months. MMO improved in both groups, with PRP showing a greater increase (35.5 mm to 43.8 mm) than arthrocentesis (34.9 mm to 41.2 mm). Functional limitation scores also improved more significantly in the PRP group. Conclusion: PRP injections provided better long-term outcomes in terms of pain relief and functional improvement compared to arthrocentesis, suggesting its potential as a more effective conservative treatment for TMJ disorders.

Authors

Institutions

Publication Details

Journal
Journal of Pharmacy And Bioallied Sciences
Published
2025-10-29
DOI
https://doi.org/10.4103/jpbs.jpbs_737_25
Primary Topic
Temporomandibular Joint Disorders
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Effectiveness of Arthrocentesis versus Platelet-Rich Plasma Injections in TMJ Disorders: A Clinical Study

Sajni Rai, Mrinal Gawali, Amit Rao, Sahana B Holla et al.
Journal of Pharmacy And Bioallied Sciences
Temporomandibular Joint Disorders
article

Effectiveness of Arthrocentesis versus Platelet-Rich Plasma Injections in TMJ Disorders: A Clinical Study

Sajni Rai, Mrinal Gawali, Amit Rao, Sahana B Holla, D Shanmugapriyan, KM Paijas
article en

Abstract

Background: Temporomandibular joint (TMJ) disorders affect a significant proportion of the population, leading to pain, joint dysfunction, and reduced quality of life. Arthrocentesis and platelet-rich plasma (PRP) injections are two widely used conservative treatments. This study aims to compare the effectiveness of arthrocentesis and PRP in improving pain relief, mouth opening, and functional outcomes in TMJ disorder patients. Methods: A total of 60 patients diagnosed with TMJ disorders were enrolled and divided into two groups ( n = 30 each). Group A underwent arthrocentesis, while Group B received PRP injections. Outcomes were measured based on pain reduction (VAS score), maximum mouth opening (maximum mouth opening [MMO] in mm), and functional improvement using the Jaw Function Limitation Scale. Measurements were recorded at baseline, 1 month, and 3 months post-treatment. Statistical analysis was conducted using paired t -tests and analysis of variance (ANOVA). Results: Both treatment groups showed significant improvement. The PRP group demonstrated superior long-term pain relief (VAS: 7.2 to 2.1) compared to arthrocentesis (VAS: 7.4 to 3.5) at 3 months. MMO improved in both groups, with PRP showing a greater increase (35.5 mm to 43.8 mm) than arthrocentesis (34.9 mm to 41.2 mm). Functional limitation scores also improved more significantly in the PRP group. Conclusion: PRP injections provided better long-term outcomes in terms of pain relief and functional improvement compared to arthrocentesis, suggesting its potential as a more effective conservative treatment for TMJ disorders.

Journal of Pharmacy And Bioallied SciencesVol. 18(2)
Nitte University (IN), Manubhai Patel Dental College and Hospital (IN), Balaji Dental & Craniofacial Hospital (IN), Government Dental College and Hospital (IN), Sri Rajiv Gandhi College of Dental Sciences and Hospital (IN)
Openalex Percentile: Top 63%
Temporomandibular Joint Disorders
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Effectiveness of Arthrocentesis versus Platelet-Rich Plasma Injections in TMJ Disorders: A Clinical Study — Sajni Rai, Mrinal Gawali, et al. · Journal of Pharmacy And Bioallied Sciences (2025) | TGRS Research Map | TGRS