Microstructural brain changes and their impact on hemorrhagic stroke recovery: a neurite orientation dispersion and density imaging-based study
MRI metrics derived from the multishell diffusion model suggest that the early stage of ICH may result in the disruption of microstructural integrity. Damage to white-matter neurons in the affected cerebral hemisphere is correlated with functional impairment, whereas damage to deep gray-matter neurons in the same hemisphere is associated with a decline in cognitive outcome.
Authors
- Ying-Jie Zhang (ORCID: https://orcid.org/0000-0002-0603-8996)
- Zhensen Chen (ORCID: https://orcid.org/0000-0001-7975-2528)
- Ying Yan (ORCID: https://orcid.org/0000-0002-1247-3302)
- Lingxu Chen (ORCID: https://orcid.org/0009-0001-7537-1362)
- Sihui Wang (ORCID: https://orcid.org/0000-0003-4735-8934)
- Shengjun Sun
- Mengyuan Yuan
- Hongwei Li (ORCID: https://orcid.org/0000-0003-1591-7674)
- He Wang (ORCID: https://orcid.org/0000-0003-4863-3280)
- Xiaochen Wang (ORCID: https://orcid.org/0000-0001-9580-9360)
- Yi Ju
- Xuening Zhao
Institutions
- Capital Medical University (CN)
- Fudan University (CN)
- Shanghai Institute for Science of Science (CN)
- Beijing Tian Tan Hospital (CN)
- Beijing Institute of Neurosurgery (CN)
- Shanghai Center for Brain Science and Brain-Inspired Technology (CN)
Publication Details
- Journal
- Quantitative Imaging in Medicine and Surgery
- Published
- 2025-10-29
- DOI
- https://doi.org/10.21037/qims-2025-510
- Citations
- 1
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.36