Benign and malignant uptake in the postoperative diagnosis of gastrointestinal tumors: a comparative study of 68Ga-FAPI-04 and 18F-FDG

<sup>68</sup>Ga-FAPI-04 PET/MRI is superior to <sup>18</sup>F-FDG PET/CT in detecting recurrent anastomotic sites and lymph node metastases. However, for other lesions, <sup>68</sup>Ga-FAPI-04 uptake provides little ability to differentiate between benign and malignant lesions. Clinicians should integrate these findings with other clinical information for optimal results.

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Publication Details

Journal
Quantitative Imaging in Medicine and Surgery
Published
2025-10-29
DOI
https://doi.org/10.21037/qims-2025-670
Primary Topic
Peptidase Inhibition and Analysis
Type
article
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article

Benign and malignant uptake in the postoperative diagnosis of gastrointestinal tumors: a comparative study of 68Ga-FAPI-04 and 18F-FDG

Yuxing Xu, Zhenpeng Yu, Dan Zhang, Pengfei Dai et al.
Quantitative Imaging in Medicine and Surgery
Peptidase Inhibition and Analysis
article

Benign and malignant uptake in the postoperative diagnosis of gastrointestinal tumors: a comparative study of 68Ga-FAPI-04 and 18F-FDG

Yuxing Xu, Zhenpeng Yu, Dan Zhang, Pengfei Dai, Jingxuan Miao, Hui Wang
article en

Abstract

<sup>68</sup>Ga-FAPI-04 PET/MRI is superior to <sup>18</sup>F-FDG PET/CT in detecting recurrent anastomotic sites and lymph node metastases. However, for other lesions, <sup>68</sup>Ga-FAPI-04 uptake provides little ability to differentiate between benign and malignant lesions. Clinicians should integrate these findings with other clinical information for optimal results.

Quantitative Imaging in Medicine and SurgeryVol. 15(11)
Anhui Medical University (CN), First Affiliated Hospital of Anhui Medical University (CN)
Openalex Percentile: Top 58%
Peptidase Inhibition and Analysis
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Benign and malignant uptake in the postoperative diagnosis of gastrointestinal tumors: a comparative study of 68Ga-FAPI-04 and 18F-FDG — Yuxing Xu, Zhenpeng Yu, et al. · Quantitative Imaging in Medicine and Surgery (2025) | TGRS Research Map | TGRS